SARS COV-2 infectious determination assay

Methods and compositions for characterizing a biological sample (e.g., including a source of infection) from a subject are provided. Methods may comprise detecting bonds of nucleic acids linked in living cells or organisms but degraded and thus unlinked in non-survivable cells or organisms, and then characterizing the subject based on the number of linked and unlinked sequences. 提供了用于表征来自受试者的生物样品(例如，包括感染源)的方法和组合物。方法可以包含检测在活细胞或有机体中连接但在不可存活细胞或有机体中降解并因此未连接的核酸的键，并且然后基于连接的和未连接的序列的数量表征所述受试者。