Triple inactivated vaccine for mycoplasma ovipneumoniae, mycoplasma filamentosa and D-type pasteurella multocida and preparation method thereof

The invention belongs to the technical field of vaccine preparation, and particularly relates to a triple inactivated vaccine for mycoplasma ovipneumoniae, mycoplasma filamentosa and D-type pasteurella multocida and a preparation method thereof. The triple inactivated vaccine prepared by adding an i...

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Hauptverfasser: ZHAO SHIHUA, BAI FAN, LIU SHUANGYI, LIU WEI, ZHANG YUEMEI, WANG NA, SONG YUE, QIAN LINNA, ZHANG FAN, LI XIAOYAN, FENG YING, DAI LINGLI, LI ZHI, ZHOU YUAN, DALAI BAOLIGE, YANG BIN, WANG GENYUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of vaccine preparation, and particularly relates to a triple inactivated vaccine for mycoplasma ovipneumoniae, mycoplasma filamentosa and D-type pasteurella multocida and a preparation method thereof. The triple inactivated vaccine prepared by adding an inactivated bacterium solution of mycoplasma ovipneumoniae MOBM13D004, an inactivated bacterium solution of mycoplasma filamentous MmNM02, an inactivated bacterium solution of D-type pasteurella multocida PmD100 and an immunologic adjuvant not only can prevent sheep and goat mixed infection type contagious pleuropneumonia, but also can assist in preventing goat mastitis, arthritis and the like. 本发明属于疫苗制备的技术领域,具体涉及一种绵羊肺炎支原体、丝状支原体和D型多杀性巴氏杆菌三联灭活疫苗及制备方法。通过添加绵羊肺炎支原体MO_BM13D004的灭活菌液、丝状支原体Mm_NM02的灭活菌液、D型多杀性巴氏杆菌PmD100的灭活菌液和免疫佐剂制备的三联灭活疫苗,不仅能够预防绵羊、山羊混合感染型传染性胸膜肺炎,还能协助预防山羊乳腺炎和关节炎等。