Dihydroxynaphthoic acid pyraclozine praziquantel tablet and preparation method thereof
According to the preparation method of the pyrantel pamoate praziquantel tablet, the dry starch in a certain proportion and pyrantel pamoate and praziquantel in the raw materials are subjected to a pretreatment process of co-grinding to a certain particle size, compared with an existing sieving and...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | According to the preparation method of the pyrantel pamoate praziquantel tablet, the dry starch in a certain proportion and pyrantel pamoate and praziquantel in the raw materials are subjected to a pretreatment process of co-grinding to a certain particle size, compared with an existing sieving and mixing mode, the expressed dissolution effect is better, the dissolution behaviors of the two drugs are consistent, and the preparation process is simple. According to the present invention, the two drugs in the tablet can safely and stably provide the expelling and killing effects without increasing the drug use amount, the dissolution effect is improved while the particle size requirements on the pyrantel pamoate and the praziquantel are reduced, the electrostatic interaction generated during the screening process of the praziquantel is avoided by using the co-grinding manner, and the drug use amount is not increased; the content uniformity and the quality stability of praziquantel are improved. The tablet provid |
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