Use of cyclosporine analogs as antithrombotic agents

The disclosure includes methods, compositions, and kits suitable for preventing/treating thromboembolic disorders, preventing/reducing thrombus formation, and reducing/inhibiting procoagulant platelet formation. The methods comprise administering to a subject in need thereof a composition comprising a cyclosporin analogue (e.g., CRV431). The compositions and kits comprise a cyclosporin analogue. 本文公开的内容包括适合用于预防/治疗血栓栓塞性紊乱、防止/减少血栓的形成和减少/抑制促凝血血小板形成的方法、组合物和试剂盒。所述方法包括向有相应需要的受试者施用包含环孢菌素类似物(例如，CRV431)的组合物。所述组合物和试剂盒包含环孢菌素类似物。