Crystal form of JAK2 inhibitor and preparation method thereof

The invention belongs to the technical field of medicinal chemistry, and particularly relates to crystal forms A, B, C and D of 2-{N-[4-(4-methyl) piperazine] phenyl} amino-5, 6-dihydro-7-[3-(N-tert-butyl) sulfonamide] phenyl-pyrrolo [2, 3-d] pyrimidine dihydrochloride and a preparation method thereof. The four crystal forms A, B, C and D provided by the invention can be prepared under various different conditions, the crystallization process has a good purification effect and has the beneficial characteristics of stable process, easiness in operation and the like, the preparation method of the crystal forms is simple and low in cost, and different crystal forms of 2-{N-[4-(4-methyl) piperazine] phenyl} amido-5, 6-diazabicyclo [1, 2-a] pyrimidine-2-one, which are high in purity, good in solubility and good in stability, can be obtained. The compound is 2, 6-dihydro-7-[3-(N-tert-butyl) sulfonamido] phenyl-pyrrolo [2, 3-d] pyrimidine dihydrochloride. 本发明属于药物化学技术领域，具体涉及2-{N-[4-(4-甲基)哌嗪]苯基}胺基-5,6-二氢-7-[3-(N-叔丁基)磺