Preparation method of gel for gingival filling and regeneration

The invention discloses a preparation method of gel for gingival filling and regeneration, which specifically comprises the following steps: extracting impurity-removed protein and antigen-removed collagen, preparing cross-linked hyaluronic acid, cross-linking the impurity-removed protein and the an...

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Hauptverfasser: GU YING, ZHANG WENHAO, XU LIXIN, CAI FEIXIANG, YIN MANQI, SUN HUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a preparation method of gel for gingival filling and regeneration, which specifically comprises the following steps: extracting impurity-removed protein and antigen-removed collagen, preparing cross-linked hyaluronic acid, cross-linking the impurity-removed protein and the antigen-removed collagen with the hyaluronic acid, adding pigments with gingival effect and adding growth factors, the method comprises the following steps: grinding bovine achilles tendons, digesting the ground bovine achilles tendons by using trypsin, performing impurity protein removal treatment, centrifuging, salting out, dialyzing and adding Mg < + >, thereby obtaining the collagen with impurity protein removed and antigen removed. According to the invention, the antibacterial component Mg < + > is added, so that the complex oral environment is resisted; the whole body has good anti-pressure capability and can resist stress caused by various activities such as speaking, chewing and swallowing processes; by adopt