Prazole enteric-coated pellet and preparation method thereof

The invention discloses a prazole enteric-coated pellet and a preparation method thereof. The prazole enteric-coated pellet comprises a drug-containing pellet core, an isolating layer and an enteric-coated layer, wherein the isolating layer and the enteric-coated layer sequentially coat the drug-containing pellet core; wherein the enteric-coated layer is prepared from the following components in parts by mass: 3.20 to 4.80 parts of polyacrylic resin latex solution, 0.34 to 0.65 part of triethyl citrate, 0.19 to 0.29 part of talcum powder and 3.04 to 9.14 parts of purified water. According to the invention, the polyacrylic resin latex solution (enteric type), the triethyl citrate with high proportion and the talcum powder with low proportion are combined for use, so that the problem of pellet sticking caused by too sticky feed liquid in the pellet enteric coating preparation process can be solved; the plasticity of the enteric-coated layer can be greatly improved, so that the acid resistance problem caused by