Preparation method and application of intragastric volume-occupying hydrogel particles for obesity intervention

The invention discloses a preparation method and application of intragastric volume-occupying hydrogel particles for obesity intervention, and belongs to the technical field of hydrogel, the preparation method comprises the following steps: (1) dissolving water-soluble polysaccharide macromolecules...

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Hauptverfasser: CHEN LEI, ZHOU SHILIN, NIE JINGJIE, WANG ZHE, JI CHUANPAO
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creator CHEN LEI
ZHOU SHILIN
NIE JINGJIE
WANG ZHE
JI CHUANPAO
description The invention discloses a preparation method and application of intragastric volume-occupying hydrogel particles for obesity intervention, and belongs to the technical field of hydrogel, the preparation method comprises the following steps: (1) dissolving water-soluble polysaccharide macromolecules to obtain a polysaccharide aqueous solution; (2) a cross-linking agent solution is added into the polysaccharide aqueous solution, high-pressure homogenization is carried out, a composite solution is obtained, the adding speed of the cross-linking agent solution is 1-3 ml/min, and the pressure of high-pressure homogenization is 10000-1300 psi; and (3) drying and crushing the composite solution to obtain the intragastric volume hydrogel particles. The super-hydrophilic porous hydrogel particles are prepared by controlling the adding speed of the cross-linking agent solution and the pressure of high-pressure homogenization. Experiments prove that the intragastric volume hydrogel particles have high water absorption s
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subjects FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title Preparation method and application of intragastric volume-occupying hydrogel particles for obesity intervention
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