Capsule type drug-containing biological matrix freeze-drying reagent as well as preparation method and application thereof

The invention relates to the field of biological detection, and provides a preparation method of a capsule type drug-containing biological matrix freeze-drying reagent, which comprises the following steps: S1, carrying out freeze-drying treatment on a biological matrix; s2, uniformly mixing the medicine with the capsule shell raw materials to prepare a medicine-containing capsule shell; and S3, filling the drug-containing capsule shell with the biological matrix subjected to freeze-drying treatment, so as to obtain the capsule type drug-containing biological matrix freeze-drying reagent. Wherein the biological matrix comprises one of blood, urine or tissue homogenate; the medicine comprises at least one of barbital and phenobarbital; according to the technical scheme of freeze drying, the biological matrix is subjected to low-temperature dehydration, and the biological activity of the biological matrix is kept to the maximum extent; the medicine is added into the capsule raw materials to prepare the capsule s