Monoclonal antibody for resisting I-type human parainfluenza virus as well as preparation method and application of monoclonal antibody

The invention relates to the technical field of in-vitro detection, in particular to an anti-I human parainfluenza virus monoclonal antibody as well as a preparation method and application thereof. The monoclonal antibody provided by the invention can recognize the HN protein of the human parainflue...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FU GUANGYU, DAI CHUNYING, WANG YIFAN, YANG ZENGLI, CAO PANFEI, WU XUEWEI, HOU PENGYUN, DU PEIPEI, LI GUILIN, ZHANG WENYI, ZHAO QIAOHUI
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the technical field of in-vitro detection, in particular to an anti-I human parainfluenza virus monoclonal antibody as well as a preparation method and application thereof. The monoclonal antibody provided by the invention can recognize the HN protein of the human parainfluenza virus, and has the characteristics of good specificity, high titer and the like. A double-antibody sandwich method or a reagent and a kit for detecting the human parainfluenza virus I developed on the basis of the monoclonal antibody for resisting the human parainfluenza virus I are shorter in time consumption and higher in efficiency, and have a wide application prospect in early diagnosis and clinical diagnosis of respiratory diseases. 本发明涉及体外检测技术领域,具体涉及抗I型人副流感病毒单克隆抗体及其制备方法和应用。本发明提供的单克隆抗体,能够识别人副流感病毒HN蛋白,具有特异性好、效价高等特点。基于本发明中的抗I型人副流感病毒单克隆抗体开发的检测I型人副流感病毒的双抗夹心法或试剂、试剂盒用时更短、效率更高,在呼吸道疾病的早期诊断和临床诊断中具有广阔的应用前景。