Method for improving astragalus mongholicus embedding rate

The invention provides a method for improving the embedding rate of astragalus membranaceus, and belongs to the technical field of traditional Chinese medicine, and the method comprises the following steps: carrying out superfine grinding on the traditional Chinese medicinal material astragalus memb...

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Bibliographische Detailangaben
Hauptverfasser: ZHENG ZIYUE, JIN JIAYI, ZHANG MENG, ZHA CHUNWANG, LIU LIANGJING, FAN RONG, XU YANGE, WU XIUYUN, LI HAOYANG, LIU BINGMIAO, DING ZHENGWEN, LIU TAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a method for improving the embedding rate of astragalus membranaceus, and belongs to the technical field of traditional Chinese medicine, and the method comprises the following steps: carrying out superfine grinding on the traditional Chinese medicinal material astragalus membranaceus, carrying out deacetylation modification treatment on chitosan, then carrying out double-layer embedding on superfine powder by using sodium alginate and deacetylated chitosan, and carrying out ultrasonic spraying-vacuum freeze drying to obtain the astragalus membranaceus embedding powder. The milkvetch root sustained-release microcapsule prepared by the method disclosed by the invention solves the problems of poor drug stability, high irritation, short biological half-life period, fast in-vivo metabolic degradation, limited bioavailability and short curative effect duration after traditional Chinese medicinal materials are subjected to superfine grinding, and the embedding rate of the microcapsule is rema