Antibody for resisting extracellular vesicle membrane protein PD-L1 as well as preparation method and application thereof

The invention discloses an antibody for resisting extracellular vesicle membrane protein PD-L1 as well as a preparation method and application thereof, the amino acid sequence of a heavy chain variable region of the antibody is SEQ ID NO.1, the amino acid sequence of a light chain variable region of the antibody is SEQ ID NO.2, the antibody is obtained by immunizing an animal with the extracellular vesicle membrane protein PD-L1, and the antibody can be used for preparing an antibody for resisting extracellular vesicle membrane protein PD-L1. The affinity and the specificity on the extracellular vesicle membrane protein PD-L1 are very high. 本发明公开了一种抗细胞外囊泡膜蛋白PD-L1的抗体及其制备方法和应用，该抗体的重链可变区的氨基酸序列为SEQ ID NO.1，其轻链可变区的氨基酸序列为SEQ ID NO.2，该抗体通过细胞外囊泡膜蛋白PD-L1免疫动物获得，对细胞外囊泡膜蛋白PD-L1具有很高的亲和力和特异性。