Porphyromonas gingivalis Mfa1 monoclonal antibody and application thereof

The invention discloses a porphyromonas gingivalis Mfa1 monoclonal antibody and an application of the porphyromonas gingivalis Mfa1 monoclonal antibody. The invention provides three hybridoma cells, the three hybridoma cells are named as 2D9B9, 2F5F8 and 3B2F7, the hybridoma cells secrete three Mfa1 monoclonal antibodies, and the Mfa1 monoclonal antibodies comprise heavy chain variable regions of three CDRs and light chain variable regions of three CDRs. The invention also discloses a nucleic acid molecule for coding the antibody, a vector, a host cell and application thereof. According to the present invention, the experimental research results show that the Mfa1 monoclonal antibody can significantly inhibit the adhesion effect of P.gingivalis, can reduce the alveolar bone resorption, and can alleviate periodontitis; the Mfa1 monoclonal antibody drug provides more drug choices for patients infected with the P.gingivalis, and the Mfa1 monoclonal antibody drug has a wide application prospect. 本发明公开了牙龈卟啉单胞菌Mfa1