Display substrate

The invention provides a display substrate which comprises a substrate body, and the substrate body comprises a hole opening area, an isolation area arranged around the hole opening area and a display area arranged around the isolation area. The isolation region comprises a passivation layer arranged on one side of the substrate, at least one metal isolation column, and an organic light-emitting functional layer and an inorganic packaging layer which are sequentially arranged on the passivation layer and the metal isolation column in a stacked mode. The passivation layer comprises a retaining wall arranged around the metal isolation column, the retaining wall is configured to shield part of the side face area, close to the substrate, of the metal isolation column, and the height, perpendicular to the substrate, of the retaining wall is smaller than that of the metal isolation column. A gap is formed between one end, far away from the substrate, of the retaining wall and the metal layer, located on the top lay