Self-assembly micro-precipitation composition, skin gel thereof, preparation method and application of self-assembly micro-precipitation composition and skin gel

The invention discloses a self-assembly micro-precipitation composition, skin gel thereof, a preparation method and application, and belongs to the technical field of pharmacy. The preparation method of the self-assembly micro-precipitation composition comprises the following steps: preparing a radix gentianae water decoction solution, preparing a licorice root water decoction solution, preparing an alcohol extract of licorice root dregs, and preparing the self-assembly micro-precipitation composition. The preparation method has the following advantages: the particle size distribution is relatively uniform, and the system is relatively stable; the average particle size is 100-800 nm, the PDI is 0.05-0.40, and the potential absolute value is 20-60 mV; sEM shows that the shape is spherical; the skin gel has good biocompatibility, and the traditional Chinese medicine micro-precipitation composition in the gel can regulate and control an IL-6/JAK2/STAT3 signal channel, so that proliferation of inflammatory cells