Preparation method of isoniazide injection
The invention provides a preparation method of an isoniazide injection, each unit preparation of the isoniazide injection contains 100mg of isoniazide, 18.2 mg of sodium chloride, 2ml of water for injection and a proper amount of hydrochloric acid, and the preparation method comprises the following...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides a preparation method of an isoniazide injection, each unit preparation of the isoniazide injection contains 100mg of isoniazide, 18.2 mg of sodium chloride, 2ml of water for injection and a proper amount of hydrochloric acid, and the preparation method comprises the following steps: filling nitrogen into the water for injection at 25-55 DEG C from the upper part, the lower part and the periphery of a preparation tank through multiple pipelines, adding sodium chloride, and stirring to completely dissolve; when the dissolved oxygen in the water is detected to be lower than 5ppm, adding isoniazide, after the isoniazide is completely dissolved, adjusting the pH value to 6.0-7.5 by using hydrochloric acid, filling nitrogen into an empty ampoule bottle, then filling liquid medicine, filling nitrogen, sealing the ampoule bottle by melting, and carrying out moist heat sterilization.
本发明提供一种异烟肼注射液的制备方法,所述异烟肼注射液的每个单位制剂中含有异烟肼100mg、氯化钠18.2mg、注射用水2ml以及适量盐酸,所述制备方法包括如下步骤:通过多管路从配制罐的上下以及四周多角度向25℃-55℃注射用 |
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