Neurohormone-metal organic framework composite material as well as preparation method and application thereof

The invention discloses a neurohormone-metal organic framework composite material and a preparation method and application thereof, the metal organic framework composite material is a zeolite imidazate framework compound, preferably ZIF-8, the neurohormone is DHEA, and the neurohormone-metal organic...

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Bibliographische Detailangaben
Hauptverfasser:	YAN XINGXING, LIANG GENMING, ZHAO QIHE, CHEN QIANSONG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The invention discloses a neurohormone-metal organic framework composite material and a preparation method and application thereof, the metal organic framework composite material is a zeolite imidazate framework compound, preferably ZIF-8, the neurohormone is DHEA, and the neurohormone-metal organic framework composite material is a DHEA-ZIF-8 compound. The prepared DHEA-ZIF-8 compound can be applied to myopia prevention and control, can effectively load DHEA, has the effects of continuously releasing DHEA, inhibiting eye axis growth and delaying myopia progress, and has the characteristics of economy, safety and effectiveness. 本发明公开了一种神经激素-金属有机骨架复合材料及其制备方法和应用，其中，该金属有机骨架复合材料为沸石咪唑酯骨架化合物，优选为ZIF-8，该神经激素为DHEA，该神经激素-金属有机骨架复合材料为DHEA-ZIF-8复合物。本发明所制备获得的DHEA-ZIF-8复合物可应用于近视防控中，可以有效负载DHEA，并具有可持续释放DHEA，抑制眼轴增长，延缓近视进展的作用，且具有经济、安全有效的特点。