Application of bifidobacterium breve B.breve lw01 in preparation of medicine for preventing and/or treating colitis and colitis cancer transformation

The invention belongs to the technical field of biology. The invention provides an application of bifidobacterium breve B.brevelw01 in preparation of a medicine for preventing and/or treating colitis and colitis cancer transformation. The invention also provides a medicament for treating and/or preventing colitis and colitis cancer transformation. Under the action of the bifidobacterium breve B.brevelw01, the infiltration of colonic macrophages is reduced, and the proportion of mature macrophages in the infiltrated macrophages is increased; the specific metabolite of the bifidobacterium breve B.brevelw01 can inhibit inflammatory differentiation of macrophages by activating Akt signal channels of the macrophages, and can also inhibit inflammatory cancer transformation by adjusting differentiation of the macrophages on the intrinsic layer of intestinal tracts. The function exertion of the bifidobacterium breve B.virve lw01 partially depends on the regulation of intestinal flora. 本发明属于生物技术领域。本发明提供了短双歧杆菌B.brevelw