Application of natural product in preparation of medicine for treating autoimmune diseases

The invention discloses application of a natural product in preparation of a medicine for treating autoimmune diseases, and belongs to the field of biological medicine. The natural product Ruscogenin disclosed by the invention is one of main sapogenin and active ingredients in the traditional Chinese medicine radix ophiopogonis, and has a good anti-inflammatory effect. Experimental results show that the Ruscogenin can significantly inhibit Th17 cell differentiation, inhibit expression of Th17 cell related inflammatory factors such as IL-17A and GM-CSF, reduce transcription levels of genes such as Il17a, Il17f, Il21, Il23r, Irf4 and Rorc, and significantly relieve disease symptoms of an ulcerative colitis mouse model, so that the Ruscogenin has a function of treating autoimmune diseases. The invention provides the new application of the natural product Ruscogenin in preparation of the medicine for treating the autoimmune diseases, broadens the medical application of the Ruscogenin, and has important clinical s