Cold-resistant and high-temperature-resistant soft capsule skin as well as preparation method and application thereof

The invention discloses a cold-resistant and high-temperature-resistant soft capsule shell as well as a preparation method and application thereof, and the cold-resistant and high-temperature-resistant soft capsule shell comprises the following raw materials in percentage by weight: 14-17% of gelati...

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Bibliographische Detailangaben
Hauptverfasser: WEI SHISONG, ZHU XIAOLONG, HUANG HONGHUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a cold-resistant and high-temperature-resistant soft capsule shell as well as a preparation method and application thereof, and the cold-resistant and high-temperature-resistant soft capsule shell comprises the following raw materials in percentage by weight: 14-17% of gelatin, 6-8% of starch, 25-35% of glycerol, 40-50% of water and 2-4% of modified polyethylene glycol, the modified polyethylene glycol is prepared from preparation raw materials including polyethylene glycol and 5-norbornene-2-carboxylic acid, and the relative molecular weight of the polyethylene glycol is 400 to 800. 5-norbornene-2-carboxylic acid is used for modifying polyethylene glycol and is used for preparing the cold-resistant and high-temperature-resistant soft capsule skin, so that the self-oxidation property of gelatin is effectively reduced, the self-crosslinking reaction of the gelatin is inhibited, the soft capsule is dissolved out and disintegrated in time when entering gastric juice or intestinal juice, a