Pyrimidine compound, composition and medical application thereof

The present disclosure relates to a class of pyrimidine compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, stereoisomers, solvates and hydrates thereof. The present disclosure also relates to a process for preparing these pyrimidine compounds, pharmaceutical compositions containing them and pharmaceutical uses thereof. 本公开涉及一类嘧啶化合物、其立体异构体、互变异构体、药学上可接受的盐、立体异构体、溶剂化物和水合物。本公开还涉及一种制备这些嘧啶化合物的方法、含有它们的药物组合物及其医药应用。