PRAME-BINDING MOLECULES

The present invention addresses the problem of providing a PRAME-binding molecule comprising: a heavy chain variable region containing a heavy chain CDR1 comprising an amino acid sequence represented by SEQ ID NO: 1, a heavy chain CDR2 comprising an amino acid sequence represented by SEQ ID NO: 2, and a heavy chain CDR3 comprising an amino acid sequence represented by SEQ ID NO: 3; and/or a light chain variable region comprising a light chain CDR1 comprising the amino acid sequence represented by SEQ ID NO: 9, a light chain CDR2 comprising the amino acid sequence represented by SEQ ID NO: 10, and a light chain CDR3 comprising the amino acid sequence represented by SEQ ID NO: 11. 本发明的课题在于提供PRAME结合性分子，该课题通过如下的PRAME结合性分子解决，该PRAME结合性分子包括：含有包含序列编号1所示的氨基酸序列的重链CDR1、包含序列编号2所示的氨基酸序列的重链CDR2、和包含序列编号3所示的氨基酸序列的重链CDR3的重链可变区；和/或含有包含序列编号9所示的氨基酸序列的轻链CDR1、包含序列编号10所示的氨基酸序列的轻链CDR2、和包含序列编号11所示的氨基酸序列的轻链CDR3的轻链可变区。