Designed bacterial compositions for treatment of graft versus host disease

Provided herein are bacterial compositions useful for the treatment and prevention of complications and side effects associated with a disease or condition, such as those associated with immunosuppression, including, for example, infection and/or GvHD in a HSCT subject. The bacterial compositions di...

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Hauptverfasser: NARENDAR PREM, BALDAN, KONSTANTIN, BALASUBRAMANIAN DEEPAK, KAISER, KLAUS, HALVORSEN ERIC, VULIC MARIN, NANDAKUMAR MADHUMITHA, O 'BRIEN EDWARD J, DATTA, SUDHIN, PINA ASAF, MARTINEZ, ALEJANDRO, LOMBARDO MARIE-JOSE, SALAH, MAHMOUD, HENN MATTHEW R, FORD CHRISTOPHER B
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are bacterial compositions useful for the treatment and prevention of complications and side effects associated with a disease or condition, such as those associated with immunosuppression, including, for example, infection and/or GvHD in a HSCT subject. The bacterial compositions disclosed herein are designed to exhibit one or more functional profiles for the treatment of such diseases and disorders. 本文提供了细菌组合物,所述细菌组合物可用于治疗和预防与疾病或病症相关的并发症和副作用,诸如与免疫抑制相关的那些,包括例如HSCT受试者中的感染和/或GvHD。本文公开的细菌组合物被设计为表现出用于治疗此类疾病和病症的一种或多种功能特征。