Anti-Intestinal protein OCI-5 antibody and application thereof

The invention relates to the technical field of biological medicine, in particular to an anti-Intestinal protein OCI-5 antibody and application thereof, the code names of the anti-Intestinal protein OCI-5 antibody are B174-V33 and B174-V34, and a heavy chain variable region of the anti-Intestinal protein OCI-5 antibody comprises a CDR-H1 with an amino acid sequence as shown in SEQ ID No. 1, a CDR-H2 with an amino acid sequence as shown in SEQ ID No. 2 and a CDR-H3 with an amino acid sequence as shown in SEQ ID No. 3 or 23. According to the present invention, the anti-Intestinal protein OCI-5 antibody has high affinity and high specificity, can effectively target the tumor antigen Intestinal protein OCI-5, can be used to prepare the chimeric antigen receptor, and further can be used to prepare the chimeric antigen recipient cell, and the chimeric antigen recipient cell can efficiently kill tumor cells, and has high specificity. 本发明涉及生物医药技术领域，特别是涉及一种抗Intestinal protein OCI-5抗体及其应用，所述抗Intestinal protein OCI-5抗体代