Pharmaceutical composition for sensitizing drug-resistant bacteria and application of pharmaceutical composition

The invention relates to a pharmaceutical composition for sensitizing drug-resistant bacteria and application of the pharmaceutical composition. The pharmaceutical composition comprises carbapenem antibiotics and reduced glutathione, the mass ratio of the carbapenem antibiotics to the reduced glutathione in the composition is 1: (1-390). A trace checkerboard dilution method, a time sterilization curve and an in-vivo infection and treatment evaluation test prove that the reduced glutathione can effectively recover the sensitivity of NDM positive drug-resistant bacteria to meropenem, and systematically evaluates the in-vivo and in-vitro effectiveness of combined use of the reduced glutathione and the NDM positive drug-resistant bacteria. Therefore, the reduced glutathione can be used for preparing a preparation for recovering the sensitivity of NDM positive drug-resistant bacteria to carbapenem antibiotics. Therefore, the composition composed of the reduced glutathione and the meropenem provides a new technical