Application of mycophenolic acid in preparation of medicine for treating esophageal cancer

The invention relates to the technical field of medicines, and particularly discloses application of mycophenolic acid in preparation of a medicine for treating esophageal cancer. The invention provides the application of mycophenolic acid in preparation of the medicine for treating esophageal cance...

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Hauptverfasser: DING TONGJING, ZHANG JIAHUI, SHANG YU, CHEN JIAQI, CHEN DONG, ZHANG ZEHAN, KONG WEIJIA, CHEN MENGYUAN, WANG YUE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of medicines, and particularly discloses application of mycophenolic acid in preparation of a medicine for treating esophageal cancer. The invention provides the application of mycophenolic acid in preparation of the medicine for treating esophageal cancer for the first time, and research finds that the main action mechanism of mycophenolic acid in treatment of esophageal cancer is as follows: the mycophenolic acid can inhibit the glycolysis energy supply level of esophageal squamous cell carcinoma KYSE150 and KYSE170 so as to inhibit the cell viability and multiplication capacity of the KYSE150 and KYSE170, retard the cell cycle at the G0/G1 phase, inhibit cell migration and inhibit the esophageal cancer. And cell apoptosis is induced. The application of mycophenolic acid in esophageal squamous cell carcinoma provided by the invention is expected to provide a promising treatment scheme for esophageal squamous cell carcinoma patients, and has great clinical signifi