Preparation method of grapefruit peel essential oil nanoemulsion and application of grapefruit peel essential oil nanoemulsion in acne inflammation treatment

The invention belongs to the field of preparation and application of essential oil, and particularly relates to preparation of grapefruit peel essential oil nanoemulsion and application of the grapefruit peel essential oil nanoemulsion in the aspect of acne inflammation treatment. The invention discloses a preparation method of a Changshan Huyou peel essential oil nanoemulsion. The preparation method comprises the following steps: preparing a composite surfactant from Span-80 and Tween-80; the preparation method comprises the following steps: by taking CHEO as an oil phase and distilled water as a water phase, firstly mixing the oil phase with a surfactant, and then adding the water phase under a magnetic stirring condition to form a system; magnetically stirring and mixing the system for 1.5-2.5 hours to obtain an emulsion; and homogenizing the obtained emulsion to obtain the CHEO nano-emulsion. The invention also provides application of the citrus dichroa peel essential oil nanoemulsion prepared by the meth