Nebivolol hydrochloride composition and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to a nebivolol hydrochloride composition and a preparation method thereof, and the nebivolol hydrochloride composition is prepared from the following raw materials: nebivolol hydrochloride, a filler, hydroxypropyl methylcellulose, polysorbate 80, a disintegrating agent, colloidal silicon dioxide, magnesium stearate, lauryl sodium sulfate and a pigment. The preparation process comprises the following steps: crushing the raw materials; adding an adhesive into the crushed raw materials, drying, and adding auxiliary materials to prepare particles; according to the preparation method, the granules are pressed and formed by adopting a tablet press to obtain the nebivolol hydrochloride composition, the prepared nebivolol hydrochloride composition has the characteristics of uniform granulation and small individual difference of tablet weight, and the influence on industrial production caused by non-uniform granulation granules