Ophthalmic composition for improving stability of easily-hydrolyzed medicine, preparation method and application

The invention discloses an ophthalmic composition for improving the stability of an easily-hydrolyzed drug, a preparation method and application, belongs to the technical field of pharmaceutical preparations, and relates to an ophthalmic drug. The active component accounts for 0.001-1.0% of the total mass of the composition, the oil phase accounts for 0.5-6.0% of the total mass of the composition, the emulsifier accounts for 0.05-3.0% of the total mass of the composition, the co-emulsion accounts for 0.1-4.0% of the total mass of the composition, the pH regulator accounts for 0.01-2.0% of the total mass of the composition, the pH buffering agent accounts for 0.01-1.0% of the total mass of the composition, the osmotic pressure regulator accounts for 0.3-3.0% of the total mass of the composition, and the balance is water. According to the invention, the lipophilic end of the easily hydrolyzable drug is embedded into the oil phase or oil-water interface of the emulsion to prepare a drug delivery system of the na