Mammal early pregnancy detection marker and application thereof
The invention discloses a protein marker for early pregnancy detection of mammals, and particularly relates to a hidden marker protein serum amyloid A of early pregnancy test paper. According to the method, a liquid chromatography-mass spectrometry (LC-MS) technology is adopted for proteome sequenci...
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| creator | XIA FAN LIU GUOSHI YIN DEPENG SHI LUTING MA WENKUI ZHANG LU GAO SHUAI JIANG BOWEN ZHAO MENGMENG JI PENGYUN |
| description | The invention discloses a protein marker for early pregnancy detection of mammals, and particularly relates to a hidden marker protein serum amyloid A of early pregnancy test paper. According to the method, a liquid chromatography-mass spectrometry (LC-MS) technology is adopted for proteome sequencing, and sample correlation is compared through Venn, sample correlation, PCA and PLS-DA analysis; carrying out protein function annotation by adopting GO, KEGG, COG and Pfam, and carrying out positioning prediction on subcells; differential proteins, protein sets and differential metabolites are calculated and counted; association analysis of proteome and transcriptome is carried out to obtain early-stage pregnant sheep serum differential protein, and a key marker protein for early-stage sheep pregnancy is screened out, so that a basis is provided for early-stage sheep pregnancy detection of unknown sheep.
本发明公开了哺乳动物早期妊娠检测的蛋白标志物，尤其涉及早期妊娠试纸隐藏标志蛋白血清淀粉样物质A。本发明使用的蛋白组测序采用液相色谱-质谱(LC-MS)技术，通过Venn、样本相关性、PCA、PLS-DA分析对样品相关性进 |
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本发明公开了哺乳动物早期妊娠检测的蛋白标志物，尤其涉及早期妊娠试纸隐藏标志蛋白血清淀粉样物质A。本发明使用的蛋白组测序采用液相色谱-质谱(LC-MS)技术，通过Venn、样本相关性、PCA、PLS-DA分析对样品相关性进</description><language>chi ; eng</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230829&DB=EPODOC&CC=CN&NR=116660542A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230829&DB=EPODOC&CC=CN&NR=116660542A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>XIA FAN</creatorcontrib><creatorcontrib>LIU GUOSHI</creatorcontrib><creatorcontrib>YIN DEPENG</creatorcontrib><creatorcontrib>SHI LUTING</creatorcontrib><creatorcontrib>MA WENKUI</creatorcontrib><creatorcontrib>ZHANG LU</creatorcontrib><creatorcontrib>GAO SHUAI</creatorcontrib><creatorcontrib>JIANG BOWEN</creatorcontrib><creatorcontrib>ZHAO MENGMENG</creatorcontrib><creatorcontrib>JI PENGYUN</creatorcontrib><title>Mammal early pregnancy detection marker and application thereof</title><description>The invention discloses a protein marker for early pregnancy detection of mammals, and particularly relates to a hidden marker protein serum amyloid A of early pregnancy test paper. According to the method, a liquid chromatography-mass spectrometry (LC-MS) technology is adopted for proteome sequencing, and sample correlation is compared through Venn, sample correlation, PCA and PLS-DA analysis; carrying out protein function annotation by adopting GO, KEGG, COG and Pfam, and carrying out positioning prediction on subcells; differential proteins, protein sets and differential metabolites are calculated and counted; association analysis of proteome and transcriptome is carried out to obtain early-stage pregnant sheep serum differential protein, and a key marker protein for early-stage sheep pregnancy is screened out, so that a basis is provided for early-stage sheep pregnancy detection of unknown sheep.
本发明公开了哺乳动物早期妊娠检测的蛋白标志物，尤其涉及早期妊娠试纸隐藏标志蛋白血清淀粉样物质A。本发明使用的蛋白组测序采用液相色谱-质谱(LC-MS)技术，通过Venn、样本相关性、PCA、PLS-DA分析对样品相关性进</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLD3TczNTcxRSE0syqlUKChKTc9LzEuuVEhJLUlNLsnMz1PITSzKTi1SSMxLUUgsKMjJTE4EC5dkpBal5qfxMLCmJeYUp_JCaW4GRTfXEGcP3dSC_PjU4oLE5NS81JJ4Zz9DQzMzMwNTEyNHY2LUAACu5jEy</recordid><startdate>20230829</startdate><enddate>20230829</enddate><creator>XIA FAN</creator><creator>LIU GUOSHI</creator><creator>YIN DEPENG</creator><creator>SHI LUTING</creator><creator>MA WENKUI</creator><creator>ZHANG LU</creator><creator>GAO SHUAI</creator><creator>JIANG BOWEN</creator><creator>ZHAO MENGMENG</creator><creator>JI PENGYUN</creator><scope>EVB</scope></search><sort><creationdate>20230829</creationdate><title>Mammal early pregnancy detection marker and application thereof</title><author>XIA FAN ; LIU GUOSHI ; YIN DEPENG ; SHI LUTING ; MA WENKUI ; ZHANG LU ; GAO SHUAI ; JIANG BOWEN ; ZHAO MENGMENG ; JI PENGYUN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116660542A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>XIA FAN</creatorcontrib><creatorcontrib>LIU GUOSHI</creatorcontrib><creatorcontrib>YIN DEPENG</creatorcontrib><creatorcontrib>SHI LUTING</creatorcontrib><creatorcontrib>MA WENKUI</creatorcontrib><creatorcontrib>ZHANG LU</creatorcontrib><creatorcontrib>GAO SHUAI</creatorcontrib><creatorcontrib>JIANG BOWEN</creatorcontrib><creatorcontrib>ZHAO MENGMENG</creatorcontrib><creatorcontrib>JI PENGYUN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>XIA FAN</au><au>LIU GUOSHI</au><au>YIN DEPENG</au><au>SHI LUTING</au><au>MA WENKUI</au><au>ZHANG LU</au><au>GAO SHUAI</au><au>JIANG BOWEN</au><au>ZHAO MENGMENG</au><au>JI PENGYUN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Mammal early pregnancy detection marker and application thereof</title><date>2023-08-29</date><risdate>2023</risdate><abstract>The invention discloses a protein marker for early pregnancy detection of mammals, and particularly relates to a hidden marker protein serum amyloid A of early pregnancy test paper. According to the method, a liquid chromatography-mass spectrometry (LC-MS) technology is adopted for proteome sequencing, and sample correlation is compared through Venn, sample correlation, PCA and PLS-DA analysis; carrying out protein function annotation by adopting GO, KEGG, COG and Pfam, and carrying out positioning prediction on subcells; differential proteins, protein sets and differential metabolites are calculated and counted; association analysis of proteome and transcriptome is carried out to obtain early-stage pregnant sheep serum differential protein, and a key marker protein for early-stage sheep pregnancy is screened out, so that a basis is provided for early-stage sheep pregnancy detection of unknown sheep.
本发明公开了哺乳动物早期妊娠检测的蛋白标志物，尤其涉及早期妊娠试纸隐藏标志蛋白血清淀粉样物质A。本发明使用的蛋白组测序采用液相色谱-质谱(LC-MS)技术，通过Venn、样本相关性、PCA、PLS-DA分析对样品相关性进</abstract><oa>free_for_read</oa></addata></record> |
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| title | Mammal early pregnancy detection marker and application thereof |
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