Metal ion slow-release nanofiber bone regeneration membrane and preparation method thereof

The invention discloses a metal ion slow-release nanofiber bone regeneration membrane and a preparation method thereof, the regeneration membrane comprises a collagenous fiber membrane, MOFs loaded on the collagenous fiber membrane, and a polycaprolactone fiber membrane positioned on one side of the...

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Hauptverfasser: ZHENG ZILI, LIU YAO, LUO EN, LYU JIACHENG, GAO CUITING, HE ZE, LI ZHONGMING, XU JIAZHUANG
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creator ZHENG ZILI
LIU YAO
LUO EN
LYU JIACHENG
GAO CUITING
HE ZE
LI ZHONGMING
XU JIAZHUANG
description The invention discloses a metal ion slow-release nanofiber bone regeneration membrane and a preparation method thereof, the regeneration membrane comprises a collagenous fiber membrane, MOFs loaded on the collagenous fiber membrane, and a polycaprolactone fiber membrane positioned on one side of the collagenous fiber membrane loaded with the MOFs, the polyethylene glycol-polycaprolactone segmented copolymer layer is positioned on one side, far away from the MOFs, of the polycaprolactone layer. The outer layer of the nanofiber bone regeneration membrane comprises the polycaprolactone fiber membrane and the polyethylene glycol-polycaprolactone block copolymer layer attached to the surface of the polycaprolactone fiber membrane, the combination of the polycaprolactone fiber membrane and the polyethylene glycol-polycaprolactone block copolymer layer can effectively prevent soft tissue invasion, and a good barrier effect is achieved; besides, both the polycaprolactone and the polyethylene glycol-polycaprolactone b
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
title Metal ion slow-release nanofiber bone regeneration membrane and preparation method thereof
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