Metal ion slow-release nanofiber bone regeneration membrane and preparation method thereof

The invention discloses a metal ion slow-release nanofiber bone regeneration membrane and a preparation method thereof, the regeneration membrane comprises a collagenous fiber membrane, MOFs loaded on the collagenous fiber membrane, and a polycaprolactone fiber membrane positioned on one side of the collagenous fiber membrane loaded with the MOFs, the polyethylene glycol-polycaprolactone segmented copolymer layer is positioned on one side, far away from the MOFs, of the polycaprolactone layer. The outer layer of the nanofiber bone regeneration membrane comprises the polycaprolactone fiber membrane and the polyethylene glycol-polycaprolactone block copolymer layer attached to the surface of the polycaprolactone fiber membrane, the combination of the polycaprolactone fiber membrane and the polyethylene glycol-polycaprolactone block copolymer layer can effectively prevent soft tissue invasion, and a good barrier effect is achieved; besides, both the polycaprolactone and the polyethylene glycol-polycaprolactone b