Novel polypeptides

The present disclosure relates to a class of engineered polypeptides having a binding affinity for CD69, and provides a CD69 binding polypeptide comprising the sequence EX2 X3 X4 AX6 X7 EIX10 X11 LPNLX16 X17 X18 QK X21 AFKX25 X26 LKD. The disclosure also relates to the use of such CD69 binding polypeptides as therapeutic, prognostic and/or diagnostic agents. 本披露涉及一类对CD69具有结合亲和力的工程化多肽，并且提供了包含序列EX2X3X4AX6X7EIX10X11LPNLX16X17X18QK X21AFKX25X26LKD的CD69结合多肽。本披露还涉及这种CD69结合多肽作为治疗剂、预后剂和/或诊断剂的用途。