Irreversible electroporation tissue ablation finite element model optimization method and system based on Nelder-Mead algorithm

The invention discloses an irreversible electroporation tissue ablation finite element model optimization method and system based on a Nelder-Mead algorithm. The method comprises the steps that a tumor tissue three-dimensional geometric model is established according to a medical diagnosis image of...

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Hauptverfasser: ZHANG YAPENG, ZOU CONG, SUN JIAGUO, GOU XINGHE, GUO FEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an irreversible electroporation tissue ablation finite element model optimization method and system based on a Nelder-Mead algorithm. The method comprises the steps that a tumor tissue three-dimensional geometric model is established according to a medical diagnosis image of a patient; optimizing parameters of a treatment scheme are selected, and an irreversible electroporation tissue ablation parameterized finite element model is established; performing scheme optimization through a Nelder-Mead algorithm, constructing an initial simplex according to initial parameters, calculating values of an objective function and a constraint function under each group of parameters, sorting vertexes of the simplex according to the objective function values, performing deformation operations such as reflection, expansion and contraction, and outputting optimal therapeutic scheme parameters when an iteration termination condition is reached; the method has the advantages that irregularity of tumor ti