Bionic collagen double-layer stent and preparation method thereof
The invention relates to the technical field of biomedical materials, in particular to a bionic collagen double-layer stent and a preparation method thereof.The low-price pig peritoneum serves as a raw material, and an acellular matrix with the same thickness and a compact structure as the epidermal...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to the technical field of biomedical materials, in particular to a bionic collagen double-layer stent and a preparation method thereof.The low-price pig peritoneum serves as a raw material, and an acellular matrix with the same thickness and a compact structure as the epidermal layer of human skin is prepared through a degreasing and decellularizing technology; a loose and porous hydrogel layer is further prepared by using the acellular matrix cell matrix, and a suitable microenvironment can be provided for adhesion, growth and proliferation of cells, so that the formed double-layer scaffold is closer to human tissues in structure, a microenvironment beneficial to adhesion, proliferation and differentiation of the cells is provided, and the scaffold has a good application prospect. Meanwhile, proper porosity and mechanical performance can be kept, and the technical problem that layers are prone to being separated in the actual using process of an existing double-layer support is solved. |
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