Substituted 6, 7-dihydro-5h-benzo [7] rotaxene compounds and derivatives thereof, process for their preparation and therapeutic use thereof
Disclosed herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 and R2 represent a hydrogen atom or a deuterium atom; r3 represents a hydrogen atom, a-COOH group or a-OH group; r3'and R3 ''represent a hydrogen atom, a methyl group, a methoxy gro...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | Disclosed herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 and R2 represent a hydrogen atom or a deuterium atom; r3 represents a hydrogen atom, a-COOH group or a-OH group; r3'and R3 ''represent a hydrogen atom, a methyl group, a methoxy group, a chlorine atom, a fluorine atom, or a cyano group; r4 and R5 represent a hydrogen atom, a halogen atom, a-NH2 group, a (C1-C3) alkyl group, a (C1-C3) alkoxy group, or a-OH group; or R4 and R5 together form an oxo group, or R4 and R5 together form an = NOCH3 group or a (C3-C5) cycloalkyl group; r7 represents a hydrogen atom, a methyl group, an-OH group or a fluorine atom; r6 represents a phenyl group, a fused phenyl group, a bicyclic group comprising 5 to 12 carbon atoms, a heteroaryl group comprising 2 to 9 carbon atoms and comprising from 1 to 3 heteroatoms, a cycloalkyl group comprising 3 to 7 carbon atoms, a (C3-C6) cycloalkyl (C1-C3) alkyl group, a 3 to 8 membered heterocycloalkyl group, a (C1-C6) alkyl group or a phenyl |
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