Heavy chain antibody binding to folate receptor alpha

Disclosed are anti-folate receptor alpha (FOLR1) heavy chain antibodies (e.g., UniAbsTM), as well as methods of making such antibodies, compositions comprising such antibodies, including pharmaceutical compositions, and uses thereof to treat disorders characterized by expression of folate receptor a...

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Bibliographische Detailangaben
Hauptverfasser:	KO HAIM, AVANZINO, BRUNO, TRINKLEIN NATHAN, HARRIS KATHERINE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Disclosed are anti-folate receptor alpha (FOLR1) heavy chain antibodies (e.g., UniAbsTM), as well as methods of making such antibodies, compositions comprising such antibodies, including pharmaceutical compositions, and uses thereof to treat disorders characterized by expression of folate receptor alpha (FOLR1). 披露了抗叶酸受体α(FOLR1)重链抗体(例如，UniAbsTM)，以及制备此类抗体的方法，包含此类抗体的组合物，包括药物组合物，及其治疗特征在于叶酸受体α(FOLR1)的表达的障碍的用途。