Biodegradable radioactive 90Y microsphere and preparation method thereof

The invention relates to the field of radioactive interventional therapy, in particular to biodegradable radioactive 90Y microspheres and a preparation method thereof. The biodegradable radioactive 90Y microspheres are alginate radioactive gel, the alginate radioactive gel is gel formed by crosslinking alginate sol and multivalent metal ions, and the multivalent metal ions comprise 90Y < 3 + > ions and non-radioactive multivalent metal ions. The biodegradable radioactive 90Y microsphere provided by the invention has the advantages of degradability, low radionuclide dissolution rate, good embolism effect and the like. 本发明涉及放射性介入治疗领域，尤其涉及一种可生物降解的放射性90Y微球及其制备方法。所述可生物降解的放射性90Y微球为海藻酸盐放射性凝胶，所述海藻酸盐放射性凝胶为海藻酸盐溶胶与多价金属离子交联形成的凝胶，所述多价金属离子包括90Y3+离子和非放射性的多价金属离子。本发明提供的可生物降解的放射性90Y微球具有可降解、放射性核素溶出率低、栓塞效果好等优点。