Preparation method of PDMS (polydimethylsiloxane) microneedle applying parylene

The invention discloses a preparation method of a polydimethylsiloxane (PDMS) microneedle applying parylene, which comprises the following steps: S1, coating a film on a mold: depositing a layer of parylene film convenient for demolding in a microneedle forming mold; s2, pouring: filling a room-temperature liquid PDMS tank into a microneedle mold; s3, performing high-temperature curing, namely putting the microneedle mold into a vacuum oven, vacuumizing, defoaming a sample for 10 minutes, then performing high-temperature curing at 75 DEG C for 4 hours, and cooling to room temperature; s4, demolding, and taking out the PDMS microneedle in the microneedle mold; s5, depositing a transition film, namely depositing a layer of parylene film on the PDMS microneedle in the step S4; and S6, an alloy layer is deposited, and a metal layer is deposited on the product in the step S5. By means of the mode, the PDMS microneedle is simple in structure, the PDMS microneedle can be demolded more completely, the adhesive force