Application of emodin in preparation of anti-Hantaan virus medicine

The invention belongs to the technical field of antiviral drugs, and particularly relates to application of emodin in preparation of an anti-hantaan virus drug, the in-vitro anti-hantaan virus concentration of the emodin is 25-100 [mu] M, the in-vivo anti-hantaan virus concentration of the emodin is...

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Hauptverfasser: ZHANG LIANG, LUO LULU, MA HONGWEI, ZHAO YUEXI, NIU YIFENG, LIU XIAOQIAN, ZHANG FANGLIN, WANG YANBO, CHENG LINFENG, YE WEI
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creator ZHANG LIANG
LUO LULU
MA HONGWEI
ZHAO YUEXI
NIU YIFENG
LIU XIAOQIAN
ZHANG FANGLIN
WANG YANBO
CHENG LINFENG
YE WEI
description The invention belongs to the technical field of antiviral drugs, and particularly relates to application of emodin in preparation of an anti-hantaan virus drug, the in-vitro anti-hantaan virus concentration of the emodin is 25-100 [mu] M, the in-vivo anti-hantaan virus concentration of the emodin is 25-100 mg/kg, and it is found that the emodin can inhibit transcriptional translation of HTNV viruses and can be used for preparing anti-hantaan virus products. 本发明属于抗病毒药物技术领域,具体为大黄素在制备抗汉滩病毒药物中的应用,大黄素在体外抗汉坦病毒的浓度为25-100μM,大黄素在体内抗汉坦病毒的浓度为25-100mg/kg,发现大黄素可抑制HTNV病毒的转录翻译,可用于制备抗汉坦病毒的产品。
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Application of emodin in preparation of anti-Hantaan virus medicine
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