Application of emodin in preparation of anti-Hantaan virus medicine

The invention belongs to the technical field of antiviral drugs, and particularly relates to application of emodin in preparation of an anti-hantaan virus drug, the in-vitro anti-hantaan virus concentration of the emodin is 25-100 [mu] M, the in-vivo anti-hantaan virus concentration of the emodin is...

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Hauptverfasser: ZHANG LIANG, LUO LULU, MA HONGWEI, ZHAO YUEXI, NIU YIFENG, LIU XIAOQIAN, ZHANG FANGLIN, WANG YANBO, CHENG LINFENG, YE WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of antiviral drugs, and particularly relates to application of emodin in preparation of an anti-hantaan virus drug, the in-vitro anti-hantaan virus concentration of the emodin is 25-100 [mu] M, the in-vivo anti-hantaan virus concentration of the emodin is 25-100 mg/kg, and it is found that the emodin can inhibit transcriptional translation of HTNV viruses and can be used for preparing anti-hantaan virus products. 本发明属于抗病毒药物技术领域,具体为大黄素在制备抗汉滩病毒药物中的应用,大黄素在体外抗汉坦病毒的浓度为25-100μM,大黄素在体内抗汉坦病毒的浓度为25-100mg/kg,发现大黄素可抑制HTNV病毒的转录翻译,可用于制备抗汉坦病毒的产品。