Application of 10-hydroxydecenoic acid in preparation of medicine for treating severe depression

The invention discloses an application of 10-hydroxydecenoic acid in preparation of a medicine for treating severe depression. A social contusion pressure stress induced severe depression model (CSDS) is adopted, and research finds that 10-hydroxydecenoic acid has a rapid and efficient anti-depression effect on severe depression and has obvious creativity and substantive progress in the aspects of depression types, onset time and therapeutic administration; the method has a remarkable effect in the aspects of quickly relieving social fear and relieving despair mood, and has an extremely important value in enhancing the confidence of despair diseases of depression patients. 本发明公开了10-羟基癸烯酸在制备重度抑郁治疗药物中的应用。本发明采用社交挫败压力应激诱导的重度抑郁模型(CSDS)，研究并发现10-羟基癸烯酸对重度抑郁具有快速、高效抗抑郁作用，在抑郁类型、起效时间、治疗性给药方面都具有明显创造性和实质性进步，对快速缓解社交恐惧、舒缓绝望情绪方面具有显著效应，对于抑郁病人增强战胜疾病的信心有极为重要的价值。