Preparation method of BTK degradation agent

The invention relates to a preparation method of a compound as shown in a formula (I) and an intermediate thereof. The method is mild in reaction condition, free of high-temperature and high-pressure reaction, low-toxicity or non-toxic in raw material, simple to operate, high in reaction yield, high...

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Bibliographische Detailangaben
Hauptverfasser: WANG WEI, HE YONGYAO, YI SHIXU, CHEN ZENGFEI, PAN XUSONG, LI YANLIN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a preparation method of a compound as shown in a formula (I) and an intermediate thereof. The method is mild in reaction condition, free of high-temperature and high-pressure reaction, low-toxicity or non-toxic in raw material, simple to operate, high in reaction yield, high in product purity, convenient in post-treatment, good in reproducibility and suitable for industrial production. 一种式(I)所示的化合物及其中间体的制备方法,该方法反应条件温和,不涉及高温、高压反应,原材料低毒或无毒,操作简单,反应产率高,产品纯度高,后处理方便,重现性好,适合于工业化生产。