Benzo ten-membered carbocyclic mixed-source terpene compound as well as preparation method and application thereof

The invention relates to the technical field of mixed-source terpenoids, in particular to a benzo ten-membered carbocyclic ring mixed-source terpenoids and a preparation method and application thereof. Then, soaking the mushroom sporocarp with ethyl acetate to obtain an extracting solution, and concentrating the extracting solution to obtain an extract; then, adopting normal-phase silica gel as a filler, and eluting the extract with petroleum ether-dichloromethane to obtain an eluted fraction; and finally, separating and purifying the obtained elution fraction through reversed-phase high performance liquid chromatography. The benzo ten-membered carbocyclic mixed-source terpene compound disclosed by the invention has remarkable anti-gastric cancer activity, and the preparation method is simple, environment-friendly and low in cost. 本发明涉及混源萜类化合物技术领域，是一种苯并十元碳环混源萜化合物及其制备方法和应用，该化合物是将蘑菇子实体粉碎成粉末；然后，用乙酸乙酯浸泡蘑菇子实体，得到提取液，将提取液浓缩，得到浸膏；接着，采用正相硅胶填料，用石油醚-二氯甲烷洗脱浸膏，得到洗脱馏分；最后，将所得的洗脱馏分经反相高效液相色谱进行分离纯化得到。本发明苯并十元碳环混源萜化合物具有显著抗胃癌活性，该