Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide

The invention discloses an electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide, which comprises the following step: reacting aryl sulfone or heteroaryl sulfone with aryl bromide under the action of a catalyst, a ligand and metal magnesium to obtain a target product. The preparation method disclosed by the invention has the characteristics of mild reaction conditions, simple post-treatment, green steps, low pollution, high economic benefits and the like. 本发明公开了一种芳基砜或杂芳基砜与芳基溴化物的亲电交叉偶联反应方法，将芳基砜或杂芳基砜和芳基溴化物，在催化剂、配体和金属镁的作用下反应，得到目标产物。本发明制备方法反应条件温和，具有后处理简单、步骤绿色、污染低、经济效益高等特点。