Application of chlorpromazine in preparation of coronavirus inhibitor

The invention discloses an application of chlorpromazine in preparation of a coronavirus inhibitor. The invention provides application of chlorpromazine or pharmaceutically acceptable salt thereof, which is (a) or (b) or (c) or (d) as follows: (a) application in preparation of a coronavirus inhibito...

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Hauptverfasser: MEI JIAJIA, MINEYAMA, WEI TAO, ZHAO JIANYUAN, REN LILI
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MINEYAMA
WEI TAO
ZHAO JIANYUAN
REN LILI
description The invention discloses an application of chlorpromazine in preparation of a coronavirus inhibitor. The invention provides application of chlorpromazine or pharmaceutically acceptable salt thereof, which is (a) or (b) or (c) or (d) as follows: (a) application in preparation of a coronavirus inhibitor; (b) application in inhibition of coronavirus; (c) application in product preparation; the product is used for treating diseases caused by coronavirus infection. And (d) application in treating diseases caused by coronavirus infection. Experiments prove that chlorpromazine has good anti-SARS-CoV-2 activity and/or anti-HCoV-OC43, and has an important application prospect in the treatment of SARS-CoV-2 infection and/or HCoV-OC43 infection. 本发明公开了氯丙嗪在制备冠状病毒抑制剂中的应用。本发明提供了氯丙嗪或其在药学上可接受的盐的应用,为如下(a)或(b)或(c)或(d):(a)在制备冠状病毒抑制剂中的应用;(b)在抑制冠状病毒中的应用;(c)在制备产品中的应用;所述产品的用途为治疗冠状病毒感染引起的疾病;(d)在治疗冠状病毒感染引起的疾病中的应用。本发明通过实验证明氯丙嗪具有良好的抗SARS-CoV-2活性和/或抗HCoV-OC43,具有重要的治疗SARS-CoV-2感染和/或HCoV-OC43感染的应用前景。
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Application of chlorpromazine in preparation of coronavirus inhibitor
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