Chiral oxazoline pyridine-cobalt compound as well as synthesis method and application thereof

The invention discloses a chiral oxazoline pyridine-cobalt compound and a synthesis method and application thereof.The synthesis method comprises the steps that 6-bromine-2-pyridylaldehyde serves as an initial raw material and is subjected to Suzuki coupling with arylboronic acid under the catalysis...

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Hauptverfasser: GONG JUNFANG, ZHAO JIAXING, JIANG HUI, SONG MAOPING, LIU JINKUI, NAN CHENLONG, HAO XIUGE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a chiral oxazoline pyridine-cobalt compound and a synthesis method and application thereof.The synthesis method comprises the steps that 6-bromine-2-pyridylaldehyde serves as an initial raw material and is subjected to Suzuki coupling with arylboronic acid under the catalysis of tetrakis (triphenylphosphine) palladium, and 6-aryl-2-pyridylaldehyde is obtained; and then the compound, 6-bromo-2-pyridylaldehyde or 2-pyridylaldehyde and different chiral amino alcohols are subjected to ring closing to form the corresponding 2-aryl-6-(oxazoline) pyridine ligand. The ligand is reacted with anhydrous cobalt chloride to successfully prepare the corresponding chiral metal cobalt catalyst. The metal cobalt catalyst synthesized by the invention has different chiral groups, electronic effects and steric hindrance, and can catalyze the polymerization reaction of isoprene, and when the reaction time is 2 hours, the reaction temperature is 25 DEG C, and Al/Co is 80, the molecular weight of the prepare