Fluorine ion fluorescent probe as well as synthesis method and application thereof
The invention discloses a synthesis method of a fluorine ion fluorescent probe in the technical field of biochemical analysis, which is characterized in that resorufin is used as a fluorophore, a silicon-oxygen bond is used as a recognition group, and a new synthesis route is designed to synthesize...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a synthesis method of a fluorine ion fluorescent probe in the technical field of biochemical analysis, which is characterized in that resorufin is used as a fluorophore, a silicon-oxygen bond is used as a recognition group, and a new synthesis route is designed to synthesize the fluorine ion fluorescent probe, so that the detection of fluorine ions is realized. Large instruments are not needed, operation is easy, reaction conditions are mild, convenience and high efficiency are achieved, and the fluorine ion fluorescent probe has remarkable signal response performance on fluorine ions on ultraviolet and fluorescence spectrums and can react with free fluorine of the fluorine ion fluorescent probe when applied to teeth and conduct imaging.
本发明公开了生化分析技术领域中的一种氟离子荧光探针的合成方法,其以试卤灵为荧光团,硅氧键为识别基团,设计新的合成路线合成了一种氟离子荧光探针,从而实现对氟离子的检测。本申请不需要大型仪器,操作简单,反应条件温和,便捷高效,在紫外和荧光光谱上氟离子荧光探针对氟离子有显著的信号响应性能,以及运用到牙齿上可与其游离氟发生反应并成像。 |
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