Carbonyl reductase mutant and application thereof
The invention discloses a carbonyl reductase mutant and application thereof. The reductase mutant disclosed by the invention is prepared by directional mutation of an amino acid sequence as shown in SEQ ID NO: 1. The mutant disclosed by the invention is good in catalytic activity. The e.e. Of partia...
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| creator | WANG PING XIE CHENGFU MENG XIAO ZHU LU ZHANG QING ZHU JINGYANG SHI FENG |
| description | The invention discloses a carbonyl reductase mutant and application thereof. The reductase mutant disclosed by the invention is prepared by directional mutation of an amino acid sequence as shown in SEQ ID NO: 1. The mutant disclosed by the invention is good in catalytic activity. The e.e. Of partial mutants is greater than or equal to 98% and/or the conversion rate is greater than or equal to 95%.
本发明公开了一种羰基还原酶突变体及其应用。本发明的还原酶突变体为如SEQ ID NO:1所示的氨基酸序列定向突变制备得到。本发明突变体的催化活性好。本发明的部分突变体的e.e.≥98％和/或转化率≥95％。 |
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本发明公开了一种羰基还原酶突变体及其应用。本发明的还原酶突变体为如SEQ ID NO:1所示的氨基酸序列定向突变制备得到。本发明突变体的催化活性好。本发明的部分突变体的e.e.≥98％和/或转化率≥95％。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB0TixKys-rzFEoSk0pTS5JLE5VyC0tScwrUUjMS1FILCjIyUxOLMnMz1MoyUgtSs1P42FgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8c5-hoZmpoam5hYGjsbEqAEAuU8sAw</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>WANG PING</creator><creator>XIE CHENGFU</creator><creator>MENG XIAO</creator><creator>ZHU LU</creator><creator>ZHANG QING</creator><creator>ZHU JINGYANG</creator><creator>SHI FENG</creator><scope>EVB</scope></search><sort><creationdate>20230801</creationdate><title>Carbonyl reductase mutant and application thereof</title><author>WANG PING ; XIE CHENGFU ; MENG XIAO ; ZHU LU ; ZHANG QING ; ZHU JINGYANG ; SHI FENG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116515780A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG PING</creatorcontrib><creatorcontrib>XIE CHENGFU</creatorcontrib><creatorcontrib>MENG XIAO</creatorcontrib><creatorcontrib>ZHU LU</creatorcontrib><creatorcontrib>ZHANG QING</creatorcontrib><creatorcontrib>ZHU JINGYANG</creatorcontrib><creatorcontrib>SHI FENG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG PING</au><au>XIE CHENGFU</au><au>MENG XIAO</au><au>ZHU LU</au><au>ZHANG QING</au><au>ZHU JINGYANG</au><au>SHI FENG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Carbonyl reductase mutant and application thereof</title><date>2023-08-01</date><risdate>2023</risdate><abstract>The invention discloses a carbonyl reductase mutant and application thereof. The reductase mutant disclosed by the invention is prepared by directional mutation of an amino acid sequence as shown in SEQ ID NO: 1. The mutant disclosed by the invention is good in catalytic activity. The e.e. Of partial mutants is greater than or equal to 98% and/or the conversion rate is greater than or equal to 95%.
本发明公开了一种羰基还原酶突变体及其应用。本发明的还原酶突变体为如SEQ ID NO:1所示的氨基酸序列定向突变制备得到。本发明突变体的催化活性好。本发明的部分突变体的e.e.≥98％和/或转化率≥95％。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Carbonyl reductase mutant and application thereof |
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