1, 4-dimethyl piperazine and preparation method thereof

The invention provides 1, 4-dimethyl piperazine and a preparation method thereof, and the preparation method comprises the following steps: (1) reacting N-methylethylamine salt to obtain a reactant; and (2) purifying the reactant to obtain the 1, 4-dimethyl piperazine, the N-methylethylamine salt is...

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1. Verfasser: ZANG LIJIE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides 1, 4-dimethyl piperazine and a preparation method thereof, and the preparation method comprises the following steps: (1) reacting N-methylethylamine salt to obtain a reactant; and (2) purifying the reactant to obtain the 1, 4-dimethyl piperazine, the N-methylethylamine salt is 2-chlorine-N-methylethylamine hydrochloride or 2-bromine-N-methylethylamine bromate, and the N-methylethylamine salt is 2-chlorine-N The process for preparing the 1, 4-dimethyl piperazine provided by the invention has the advantages of higher reaction activity, high stability, high selectivity, simple reaction steps, mild reaction conditions, low requirements on reaction equipment and low potential safety hazard in production, and the purity of the 1, 4-dimethyl piperazine prepared by the preparation method provided by the invention can reach 99.5%. 本发明提供一种1,4-二甲基哌嗪及其制备方法,所述制备方法包括以下步骤:(1)将N-甲基乙胺盐反应得到反应物;(2)将所述反应物提纯,得到所述1,4-二甲基哌嗪;所述N-甲基乙胺盐为2-氯-N-甲基乙胺盐酸盐或2-溴-N-甲基乙胺溴酸盐;本发明提供的制备1,4-二甲基哌嗪的工艺具有较高反应活性、高稳定性、高选择性,反应步骤简单,反应